Health disparities are costly and preventable differences in disease progression that disproportionately affect minority communities. Practices to reduce health disparities are often rooted in prevention, particularly through screening tools. Family Health History tools are screening mechanisms that explore family history to better understand how an individual’s health can be predicted or impacted. These tools are underutilized in the African American community. Contributions to underutilization include a lack of cultural tailoring in the tools, a lack of health literacy, and a lack of effective health communication. The Family Health History Study will create a culturally appropriate Family Health History toolkit to increase utilization and ultimately decrease health disparities.